Leukopaks^®

• Abelin et al. (2019) Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction. Immunity. 51(4): 766-779.

Mobilized Leukopaks^®

• Jang et al. (2020) Optimizing Lentiviral Vector Transduction of Hematopoietic Stem Cells for Gene Therapy. Gene Ther. Doi: 10.1038/s41434-020-0150-z.

Whole Bone Marrow

• Lakatos et al. (2015) Mesenchymal Stem Cells Respond to Hypoxia by Increasing Diacylglycerols. J Cell Biochem. 2: 300-307.
• Beegle et al. (2015) Hypoxic Preconditioning of Mesenchymal Stromal Cells Induces Metabolic Changes, Enhances Survival, and Promotes Cell Retention In Vivo. Stem Cells. 33(6): 1818-1828.
• Adair et al. (2016) Semi-Automated Closed System Manufacturing of Lentivirus Gene-Modified Hematopoietic Stem Cells for Gene Therapy. Nat Commun. 7: 13173.
• Kalomoiris et al. (2016) Fibroblast Growth Factor 2 Regulates High Mobility Group A2 Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells. Cell Biochem. 117(9): 2128-2137.
• Karuna et al. (2018) Identification of a WNT5A-Responsive Degradation Domain in the Kinesin Superfamily Protein KIF26B. Genes. 9(4): 196.
• Adair et al. (2018) Novel Lineage Depletion Preserves Autologous Blood Stem Cells for Gene Therapy of Fanconi Anemia Complementation Group A. Haematol. Doi:10.3324/haematol.2018.194571.
• Awan et al. (2018) FGF2 Induces Migration of Human Bone Marrow Stromal Cells by Increasing Core Fucosylations on N-Glycans of Integrins. Stem Cell Reports. S2213-6711(18)30270-30274.
• Matsui et al. (2018) Dual Role of a C-Terminally Truncated Isoform of Large Tumor Suppressor Kinase 1 in the Regulation of Hippo Signaling and Tissue Growth. DNA and Cell Biology Online publication at https://doi.org/10.1089/dna.2018.4340.
• Ramsay et al. (2019) Modeling Snyder-Robinson Syndrome in Multipotent Stromal Cells Reveals Impaired Mitochondrial Function as a Potential Cause for Deficient Osteogenesis . Sci Rep. 9: 15395 Doi:10.1038/s41598-019-51868-5.
• Panero et al. (2019) A Study of Amniotic Fluid Preparations for Mesenchymal Stem Cells with Bone Marrow Comparison. Am J Sports Med. 47(5): 1230-1235.
• Radtke et al. (2019) Sort-Purification of Human CD34⁺CD90⁺ Cells Reduces Target Cell Population and Improves Lentiviral Transduction. bioRxiv. 850479; doi: https://doi.org/10.1101/850479
• Yazdanyar et al. (2020) Effects of Intravitreal Injection of Human CD34+ Bone Marrow Stem Cells in a Murine Model of Diabetic Retinopathy. Exp Eye Res. Doi:10.1016/j.exer.2019.107865.
• Dragoo, J. and Guzman R. (2020) Evaluation of the Consistency and Composition of Commercially Available Bone Marrow Aspirate Concentrate Systems. Orthop. J. Sports Med. Doi:10.1177/2325967119893634.
• Kim, J. et al. (2020) A RUNX2 Stabilization Pathway Mediates Physiologic and Pathologic Bone Formation. Nat Commun. 11, 2289 . Doi: 10.1038/s41467-020-16038-6.

Whole Cord Blood

• Yang et al. (2016) Human Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Proliferation of PHA-Activated Lymphocytes In Vitro by Inducing CD4+CD25highCD45RA+ Regulatory T Cell Production and Modulating Cytokine Secretion. Cell Immunol. 302: 26-31.
• Yang et al. (2016) Umbilical Cord-Derived Mesenchymal Stem Cells Reversed the Suppressive Deficiency of T Regulatory Cells from Peripheral Blood of Patients with Multiple Sclerosis in a Co-Culture – a Preliminary Study. Oncotarget. 7(45): 72537-72545.

Whole Peripheral Blood

• Kozbial et al. (2018) Automated Generation of Immature Dendritic Cells in a Single-Use System. J Immunol Methods. 6(457): 53-65.
• Kozbial et al. (2018) Scale-Up of a Perfusion-Based Dendritic Cell Generation Process. Cell Gene Therapy Insights. 4(11): 1117-1130.
• Blauwkamp et al. (2019) Analytical and Clinical Validation of a Microbial Cell-Free DNA Sequencing Test for Infectious Disease. Nat Microbiol. Doi: 10.1038/s41564-018-0349-6.
• Kozbial et al. (2019) Effect of Monocyte Seeding Density on Dendritic Cell Generation in an Automated Perfusion-Based Culture System. Biochem Eng J. Doi: 10.1016/j.bej.2019.107291.
• Field et al. (2019) An Improved Multiplex Polymerase Chain Reaction (PCR) Assay for the Identification of Mosquito (Diptera: Culicidae) Blood Meals. J Med Entomol. Doi: 10.1093/jme/tjz182.
• Dragoo, J. and Guzman R. (2020) Evaluation of the Consistency and Composition of Commercially Available Bone Marrow Aspirate Concentrate Systems. Orthop. J. Sports Med. Doi:10.1177/2325967119893634.
• Sen et al. (2020) Linking indirect effects of cytomegalovirus in transplantation to modulation of monocyte innate immune function. Sci. Adv. 22 APR 2020 : EAAX9856.

Whole Maternal Blood

• Samango-Sprouse et al. (2013) SNP-Based Non-Invasive Prenatal Testing Detects Sex Chromosome Aneuploidies with High Accuracy. Prenat Diagn. 33(7): 643-649.
• Ravi et al. (2018) Validation of a SNP-Based Non-Invasive Prenatal Test to Detect the Fetal 22q11.2 Deletion in Maternal Plasma Samples. PloS One. 13(2): e0193476.

Plasma

• Yucel et al. (2019) Analytical Validation of a Single-nucleotide Polymorphism-based Donor-derived Cell-free DNA Assay for Detecting Rejection in Kidney Transplant Patients. Transplantation. 103(12): 2657-2665.

Serum

• Sen et al. (2020) Linking indirect effects of cytomegalovirus in transplantation to modulation of monocyte innate immune function. Sci. Adv. 22 APR 2020 : EAAX9856

Mononuclear Cells

• Yamada et al. (2014) G0S2 Inhibits the Proliferation of K562 Cells by Interacting with Nucleolin in the Cytosol. Leuk Res. 38: 210-217.
• Yang et al. (2016) Human Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Proliferation of PHA-Activated Lymphocytes In Vitro by Inducing CD4+CD25highCD45RA+ Regulatory T Cell Production and Modulating Cytokine Secretion. Cell Immunol. 302: 26-31.
• Yang et al. (2016) Umbilical Cord-Derived Mesenchymal Stem Cells Reversed the Suppressive Deficiency of T Regulatory Cells from Peripheral Blood of Patients with Multiple Sclerosis in a Co-Culture – a Preliminary Study. Oncotarget. 7(45): 72537-72545.
• Ishikawa et al. (2017) A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells. Mol Cancer Ther. 16: 273-284.
• Towobola et al. (2017) Novel Immunodeficient Rat Models Offers a Unique Platform for Drug Efficacy Studies in Human Tumor Xenografts. AACR-EORTC-NCI 2017 Annual Meeting Poster.
• Towobola et al. (2017) Novel Immunodeficient Rat Models Capable of Supporting the Growth of Human Tumor Xenografts. AACR 2017 Annual Meeting Poster.
• Noto et al. (2018) The SRG™ Rat: A Novel SCID Rat for Humanization Studies. AACR 2018 Annual Meeting Poster.
• Ou et al. (2019) Novel Biomanufacturing Platform for Large-Scale and High-Quality Human T Cells Production. J Biol Eng. 13: 34.
• Schillebeeckx et al. (2020) Analytical Performance of an Immunoprofiling Assay Based on RNA Models. J Mol Diagn. doi.org/10.1016/j.jmoldx.2020.01.009.
• Karim et al. (2020) Hemophilia A Inhibitor Subjects Show Unique PBMC Gene Expression Profiles That Include Up-Regulated Innate Immune Modulators. Front Immunol. 11: 1219.
• Nasu et al. (2020) Pivotal Role of the Carbohydrate Recognition Domain in Self-Interaction of CLEC4A to Elicit the ITIM-Mediated Inhibitory Function in Murine Conventional Dendritic Cells In Vitro. Internat Immunol. doi.org/10.1093/intimm/dxaa034.
• Meng et al. (2020) Targeting Autophagy Facilitates T Lymphocyte Migration by Inducing the Expression of CXCL10 in Gastric Cancer Cell Lines. Front. Oncol. doi.org/10.3389/fonc.2020.00886.

CD34+ Stem Cells

• Hudak et al. (2014) Glycocalyx Engineering Reveals a Siglec-Based Mechanism for NK Cell Immunoevasion. Nat Chem Biol. 10(1): 69-75.
• Halkias et al. (2015) Conserved and Divergent Aspects of Human T-Cell Development and Migration in Humanized Mice. Immunol Cell Biol. 93(8): 1-11.
• Cleyrat et al. (2017) Gene Editing Rescue of a Novel MPL Mutant Associated with Congenital Amegakaryocytic Thrombocytopenia. Blood Advances. 1: 1815-1826.
• Eksioglu et al. (2017) Novel Therapeutic Approach to Improve Hematopoiesis in Low Risk MDS by Targeting MDSCs with the Fc-Engineered CD33 Antibody BI 836858. Leukemia. 31(10): 2172-2180.
• Modarai et al. (2018) Efficient Delivery and Nuclear Uptake is Not Sufficient to Detect Gene Editing in CD34+ Cells Directed by a Ribonucleoprotein Complex. Mol Ther Nucl Acids. 11: 116-129.
• Takahashi et al. (2018) Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis. Front Immunol. Doi:10.3389/fimmu.2017.02017
• Cheng et al. (2019) S100A9-Induced Overexpression of PD-1/PD-L1 Contributes to Ineffective Hematopoiesis in Myelodysplastic Syndromes. Leukemia. Doi:10.1038/s41375-019-0397-9.
• Masiuk et al. (2019) PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPC with a β-Globin Lentiviral Vector. Mol Ther Methods Clin Dev. Doi:10.1016/j.omtm.2019.03.005.
• Sugimura et al. (2019) Angiocrine Factors from HUVECs Amplify Erythroid Cells. bioRxiv. 837823; doi: https://doi.org/10.1101/837823.
• Nguyen et al. (2019) A Cas9 Nanoparticle System with Truncated Cas9 Target Sequences on DNA Repair Templates Enhances Genome Targeting in Diverse Human Immune Cell Types. bioRxiv. 591719; doi: https://doi.org/10.1101/591719.
• Nguyen et al. (2020) Polymer-Stabilized Cas9 Nanoparticles and Modified Repair Templates Increase Genome Editing Efficiency. Nat Biotechnol. 38: 44–49.
• Lo et al. (2020) Potent In Vitro Activity of β-D-4ʹ-Chloromethyl-2ʹ-Deoxy-2ʹ-Fluorocytidine Against Nipah Virus. Antivir Res. doi.org/10.1016/j.antiviral.2020.104712.

Mesenchymal Stem Cells (MSCs)

• Dorcemus and Haus (2018) Growing More Cells: cGMP Culture Environments for High Yield Expansion of MSCs. Biological Industries USA, Application Note.