Peripheral Blood Leukopaks®

Leukopaks® provide enriched peripheral blood mononuclear cells (PBMC) from a single donor with low granulocyte and red blood cells as compared to buffy coats obtained from density gradient centrifugation of whole blood. This highly enriched PBMC fraction requires minimal downstream processing (i.e. Ficoll) and can be used directly for isolating high-yields of immune cells, such as CD4+ T cells, CD8+ T cells, CD19+ B cells, monocytes, and a variety of other immune cells and subsets. This allows researchers greater reproducibility of experiments from a single donor (minimizing donor-to-donor variation), a decrease in same cell variability, and scalability of experiments from a single cell type. In addition, up to 12 Leukopak collections can be performed on the same donor in a given year, providing an ample amount of PBMCs for large-scale experiments and research studies.

High-Quality Leukopaks®

  • 1x10e10 TNCs/full bag
  • Highly-enriched PBMCs
  • Low granulocyte
  • Low hematocrit
  • 0.1-0.2% CD34+ cells
  • ≥90% viability
Representative flow analysis of a peripheral blood leukopak after RCB lysis.

Customize Your Leukopak®

Our robust donor pool allows researchers the option to select specific donor criteria to suit their needs. Let us help you find the right donor.

  • 2000+ donors
  • Recallable donors
  • Donor demographics (i.e., age, weight, ethnicity, gender, blood type, etc.)
  • Donor lifestyle characteristics (i.e., BMI, smoker/non-smoker, etc.)
  • Medical history (i.e. allergies, medications, etc.)
  • HLA, RhD, and ABO typing available
  • Additional infectious disease screening (LCMV, etc.)
  • Much more…..

We Can Isolate the Cells for You

Increase reproducibility by letting our highly trained laboratory technicians isolate the primary cells from a Leukopak for you. We follow FDA CFR 21 Part 127 requirements of cGMP/cGTP regulations and employ FDA CFR 21 Part 11 data management software (ERP & QMS) that guarantees operational excellence and consistent quality products, ensuring confidence in your research.

Frequently Asked Questions

Can an apheresis donor be recalled for my experiments?

Yes, a donor is eligible to donate white blood cells every 4 weeks.

How many cells (PBMCs) can I isolate from a Leukopak®?

Usually around 8x10e<sup>9</sup> PBMCs.

Is same day delivery available?

Yes, certain locations can receive same day courier delivery. We can also provide same day air shipments.

Is LCMV testing an option?

Yes, LCMV testing can be requested on all our Leukopaks.

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