G-CSF Mobilized Leukopaks®


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Product Description

Human mobilized peripheral blood Leukopaks provide a large quantity of mononuclear cells (MNCs) that contains a rich source of hematopoietic stem cells as compared to traditional Leukopaks. This allows researchers greater reproducibility of experiments from a single donor (minimize donor-to-donor variation), increase in scalability of experiments from a single product, and a decrease in same cell variability by obtaining high yields of specific cell types.

Mobilized Leukopaks are collected from healthy IRB consented donors that are negative for HIV, HBV, and HCV from one of StemExpress’ Stem Cell Collection Centers. Mobilized peripheral blood donors are injected with 10mcs/kg/day of Granulocyte-Colony Stimulating Factor (G-CSF), which stimulates the bone marrow to produce hematopoietic stem cells and mobilizes them into the bloodstream, prior to first day of collection. Mobilized mononuclear cells are collected by a trained technician using the Spectra Optia® Apheresis System one and two days post injection. After collection, mobilized Leukopaks are checked by flow analysis to verify percentage of granulocytes, mononuclear cells, and cell viability. Each mobilized Leukopak contains 20x10e9 total nucleated cells (TNCs).

High-Quality Mobilized Leukopaks

  • Two to four week turnaround
  • Multiple collection options
  • Highly-enriched CD34+ stem cells
  • Competitive pricing
  • Low granulocyte
  • Low hematocrit

Donor Screening:

  • Historical and current medical review
  • Infectious disease screening for Hepatitis B and C and HIV 1/2
  • Confirmed negative screening by a CLIA-certified lab within 90-days of donating
  • Additional infectious disease testing available upon request
  • Certificate of Analysis provided with each sample
  • HLA-typing available upon request
  • Good Clinical Practice Standards

Diverse Donor Pool:

  • Robust donor demographics
  • Recallable donors for longitudinal studies
  • Thousands of donors with infectious disease records

Custom Orders
We work closely with our customers to provide them with the product they need. For a custom order, please call and speak to one of our sales specialists at 530-303-3828.

Format Catalog # QTY/Unit Price/Unit
Fresh MLE1031F
G-CSF @ 10mcs/kg/day x 3 Days – Apheresis Day 4
G-CSF @ 10mcs/kg/day x 3 Days – Apheresis Day 5
G-CSF @ 10mcs/kg/day x 4 Days – Apheresis Day 5
G-CSF @ 10mcs/kg/day x 4 Days – Apheresis Day 6
G-CSF @ 10mcs/kg/day x 5 Days – Apheresis Day 6
G-CSF @ 10mcs/kg/day x 5 Days – Apheresis Day 7

Product Specifications
Cell Source:Peripheral Blood
Product Type:Apheresis
Cell Types:Mononuclear Cells, Lymphocytes, Monocytes, Plasma Cells, Stem/Progenitor Cells, Dendritic Cells
Donor Attributes:HIV-, HepB-, HepC-
Viability:≥90% by Flow Cytometry
Injections:10μg/kg/day of G-CSF


Technical Resources

Product Information Sheet

Flow Data

Figure 1. Representative flow panel of fresh G-CSF mobilized leukopak. Enriched MNC population with low granulocytes (20.76%), high viability (97.65%), and high percentage of CD34+ cells (1.68%).

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