Cord Blood CD34+ Stem/Progenitor Cells, Single Donor, Frozen
$1,030
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Category: Research Products
Product Description
CD34 is a glycosylated transmembrane protein and represents a well-established marker for human hematopoietic stem and progenitor cells in peripheral blood, bone marrow, and cord blood. CD34+ cells are self-renewing, multipotent stem cells that give rise to all blood cells of the immune system through a process called hematopoiesis. As hematopoietic stem cells progress through hematopoiesis they generate the myeloid (monocytes, macrophages, granulocytes, megakaryocytes, dendritic cells, erythrocytes) and lymphoid (T cells, B cells, NK cells) lineages. The highly specialized cells that arise from hematopoietic stem cells work collaboratively in defending the body against infection and disease.
Human cord blood CD34+ stem and progenitor cells are positively selected using immunomagnetic anti-CD34 (clone QBEND10) microbeads from the mononuclear cell fraction. Isolated cells are characterized by flow cytometry prior to cryopreservation to ensure a highly pure and viable cell population.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
| Species | Human |
|---|---|
| Disease State | Healthy |
| Cell and Tissue Source | Cord Blood |
| Product Type | Primary Cells |
| Cell Type | Stem/Progenitor Cells |
| Donor Attributes | HIV-, HepB-, HepC- |
| Purity | ≥90% by Flow Cytometry |
| Viability | ≥70% by Flow Cytometry |
| Format | Frozen |
| Contains | StemSpan™ and 10% DMSO |
| Anticoagulant | CP2D |
Product Information Sheet
Certificate of Analysis
Material Safety Data Sheet
Publications
Figure 1. Representative flow data of the CD45 frequency, viability, and purity of enriched CD34+ cells from cord blood prior to cryopreservation.
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