Human bone marrow is the tissue where new blood cells are produced. It is a rich source of hematopoietic stem cells and immature cells that give rise to different lineages of mature cells, such as red blood cells, white blood cells, and platelets, within the peripheral blood. Bone marrow is also a source of mesenchymal stem cells (marrow stromal cells) that can differentiate into the connective tissue of the body. Cells from the bone marrow are used in studies pertaining to cancer research, transplantation studies, regenerative medicine, and translational medicine.

Fresh human whole bone marrow is collected from healthy IRB consented donors that are negative for HBV, HCV, and HIV. Whole bone marrow is aspirated from up to a maximum of 4 sites on the posterior iliac crest using a 30cc syringe containing the anticoagulant Na-heparin.

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