Cord Blood CD8+ Cytotoxic T Cells, Fresh
$1,350
In stock
SKU
Category: Research Products
Product Description
Human CD8+ cytotoxic T cells, also known as cytotoxic T lymphocytes, defend the body against intracellular pathogens, such as viruses and bacteria, as well as cancerous cells. CD8+ T cells distinguish infected or diseased cells from healthy cells by recognizing antigens presented by MHC class I molecules located on the surface of the inflicted cells. Once the CD8+ T cells recognize a specific antigen it releases cytotoxins that result in apoptosis of the infected or diseased cell.
Human cord blood CD8+ cytotoxic T cells are enriched by depleting cells expressing CD4, CD14, CD16, CD19, CD20, CD36, CD56, CD66b, CD123, TCRγ/δ, and CD235a from the mononuclear cell population using immunomagnetic particles leaving purified, untouched CD8+ cytotoxic T cells. Isolated cells are characterized by flow cytometry to ensure a highly pure and viable cell population.
Cord blood is collected from mothers that are negative for HIV, HepB, and HepC during pregnancy. Testing on cord blood can be provided as a custom order.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
| Species | Human |
|---|---|
| Disease State | Healthy |
| Cell and Tissue Source | Cord Blood |
| Product Type | Primary Cells |
| Cell Type | T Cells |
| Donor Attributes | Maternal HIV-, HepB-, HepC- |
| Purity | ≥85% by Flow Cytometry |
| Viability | ≥85% by Flow Cytometry |
| Format | Fresh |
| Contains | PBS with 5% FBS and 0.5% BSA |
| Anticoagulant | CP2D |
Product Information Sheet
Certificate of Analysis
Material Safety Data Sheet
Figure 1. Representative flow data of enriched CD8+ cytotoxic T cells from cord blood prior to cryopreservation.
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