Bone Marrow CD34 Depleted Mononuclear Cells, Frozen

$375
In stock
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Category: Research Products
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BM34N300C 300 million/vial $375 USD
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Product Description

Mononuclear cells (MNCs) are composed of lymphocytes (T cells, B cells, and NK cells), monocytes, dendritic cells and stem/progenitor cells. These cells are critical components of the immune system and play key roles in the humoral and cell-mediated immune responses. Mononuclear cells are commonly used in research and clinical applications in the areas of immunology, infectious disease, hematological malignancies, vaccine development, transplant therapy, and high-throughput screening.

Bone marrow MNCs are separated from whole bone marrow by a density gradient centrifugation protocol. CD34 depleted mononuclear cells are isolated by removing the CD34+ population from the MNCs using immunomagnetic separation. The CD34 depleted mononuclear cells contain less than 0.1% CD34+ cells. The presence of CD34+ cells is assessed by flow cytometry prior to cryopreservation. The isolated MNCs can be used to isolate subpopulations or used as a control for donor matched CD34+ stem cell experiments (Please request the CD34 depleted flow-through fraction upon ordering CD34+ stem cells).

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.

More Information
Species Human
Disease State Healthy
Cell and Tissue Source Bone Marrow
Product Type Primary Cells
Cell Type Mononuclear Cells
Donor Attributes HIV-, HepB-, HepC-
Purity <0.1% CD34+ Cells by Flow Cytometry
Viability ≥70% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant Na-Heparin

Product Information Sheet

Certificate of Analysis

Material Safety Data Sheet

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