Cord Blood CD4+ Helper T Cells, Frozen

$479
In stock
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CB04010C 10 million/vial $479 USD
CB04015C 15 million/vial $750 USD
CB04020C 20 million/vial $957 USD
CB04025C 25 million/vial $1,275 USD
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Product Description

Human CD4+ helper T cells express the CD4 co-receptor and play an important role in the adaptive immune system by assisting other white blood cells. These cells are activated when they are presented an antigen on the MHC class II molecule of an antigen-presenting cell (APC). Once activated, CD4+ helper T cells secrete lymphokines that assist in the activation of B cells to secrete antibodies that target specific microbes and assist in the activation of cytotoxic T cells to destroy infected target cells.

Human cord blood CD4+ helper T cells are enriched by means of negative selection. Cells expressing CD8, CD14, CD16, CD19, CD20, CD36, CD56, CD66b, CD123, TCRγ/δ, and CD235a are depleted from the cord blood mononuclear cell population using immunomagnetic particles leaving purified, untouched CD4+ helper T cells. Cell isolations are characterized by flow cytometry prior to cryopreservation to ensure a highly pure and viable cell population.

Cord blood is collected from mothers that are negative for HIV, HepB, and HepC during pregnancy. Testing on cord blood can be provided as a custom order.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.

More Information
Species Human
Disease State Healthy
Cell and Tissue Source Cord Blood
Product Type Primary Cells
Cell Type T Cells
Donor Attributes Maternal HIV-, HepB-, HepC-
Purity ≥85% by Flow Cytometry
Viability ≥70% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant CP2D

Product Information Sheet

Certificate of Analysis

Material Safety Data Sheet

 

Figure 1. Representative flow data of enriched CD4+ helper T cells from cord blood prior to cryopreservation.

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