Cord Blood CD34+ Stem/Progenitor Cells, Pooled Donors, Fresh
CD34 is a glycosylated transmembrane protein and represents a well-established marker for human hematopoietic stem and progenitor cells in peripheral blood, bone marrow, and cord blood. CD34+ cells are self-renewing, multipotent stem cells that give rise to all blood cells of the immune system through a process called hematopoiesis. As hematopoietic stem cells progress through hematopoiesis they generate the myeloid (monocytes, macrophages, granulocytes, megakaryocytes, dendritic cells, erythrocytes) and lymphoid (T cells, B cells, NK cells) lineages. The highly specialized cells that arise from hematopoietic stem cells work collaboratively in defending the body against infection and disease.
Human cord blood CD34+ stem and progenitor cells are positively selected using immunomagnetic anti-CD34 (clone QBEND10) microbeads from the mononuclear cell fraction. Pooled CD34+ cells are from two or more donors and are available in larger lots. Isolated cells are characterized by flow cytometry to ensure a highly pure and viable cell population.
Cord blood is collected from mothers that are negative for HIV, HepB, and HepC during pregnancy. Infectious disease testing, LCMV testing and HLA typing on the cord blood can be provided as a custom order.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
|Cell and Tissue Source||Cord Blood|
|Product Type||Primary Cells|
|Cell Type||Stem/Progenitor Cells|
|Donor Attributes||Maternal HIV-, HepB-, HepC-|
|Purity||≥90% by Flow Cytometry|
|Viability||≥85% by Flow Cytometry|
Product Information Sheet
Certificate of Analysis
Material Safety Data Sheet
Figure 1. Representative flow data of the CD45 frequency, viability, and purity of enriched CD34+ cells from cord blood prior to cryopreservation.