Clinical Grade Non-Transfusable Peripheral Blood CD3 Depleted T Cells, Frozen | StemExpress

Clinical Grade Non-Transfusable Peripheral Blood CD3 Depleted T Cells, Frozen

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Category: Clinical Products
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cPB03N020C 20 million/vial Inquire
cPB03N030C 30 million/vial Inquire
cPB03N040C 40 million/vial Inquire
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Product Description

Human T cells are lymphocytes that are generally characterized by the expression of CD3 on the cell surface. These cells originate in the bone marrow, migrate to the thymus to undergo maturation, and are one of the key cell types involved in cell-mediated immunity. T cells are involved in destroying invading organisms and also aid in the activation of B cells through the thymus-dependent response. There are several different subsets of T cells, including helper T cells (naïve and memory), cytotoxic T cells (naïve and memory), regulatory T cells (Tregs) and natural killer T (NKT) cells. Removal of these T cells allows for the enrichment of stem cells and effector cells, such as NK cells.

Human peripheral blood CD3+ T cells are depleted from the total cell population using direct immunomagnetic anti-CD3 beads. All cell isolation components, including reagents, tubing sets, instruments, and buffers, are manufactured and controlled under an ISO 13485 certified quality system under FDA oversight. Cell culture procedures, including open manipulation of vials, final filling, and closure of finished products, are performed inside ISO 5 air quality processing chambers located within an FDA-registered cell manufacturing facility. Isolated primary cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used to collect and separate the cells are certified clinical grade. This item is for research use only.

More Information
Species Human
Disease State Healthy
Cell and Tissue Source Peripheral Blood
Product Type Primary Cells
Cell Type Mononuclear Cells
Donor Attributes HIV-, HepB-, HepC-
Viability ≥70% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant ACD-A

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