Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD8+ Cytotoxic T Cells, G-CSF, Frozen | StemExpress

Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD8+ Cytotoxic T Cells, G-CSF, Frozen

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Category: Clinical Products
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cMLEG08010C 10 million/vial Inquire
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Product Description

Human peripheral blood CD8+ cytotoxic T cells, also known as cytotoxic T lymphocytes, defend the body against intracellular pathogens, such as viruses and bacteria, as well as cancerous cells. CD8+ T cells distinguish infected or diseased cells from healthy cells by recognizing antigens presented by MHC class I molecules located on the surface of the inflicted cells. Once the CD8 T cells recognize a specific antigen it releases cytotoxins that result in apoptosis of the infected or diseased cell.

Human mobilized peripheral blood CD8+ cells are enriched from the total cell population using direct immunomagnetic anti-CD8 beads. All cell isolation components, including reagents, tubing sets, instruments, and buffers, are manufactured and controlled under an ISO 13485 certified quality system under FDA oversight. Cell culture procedures, including open manipulation of vials, final filling, and closure of finished products, are performed inside ISO 5 air quality processing chambers located within an FDA-registered cell manufacturing facility. Isolated primary cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used to collect and separate the cells are certified clinical grade. This item is for research use only.

More Information
Species Human
Disease State Healthy
Cell and Tissue Source Peripheral Blood
Product Type Primary Cells
Cell Type T Cells
Donor Attributes HIV-, HepB-, HepC-
Purity ≥85% by Flow Cytometry
Viability ≥80% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant ACD-A
Injections 10μg/kg/day of G-CSF

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