Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD4+ Helper T Cells, Plerixafor, Frozen | StemExpress

Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD4+ Helper T Cells, Plerixafor, Frozen

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Category: Clinical Products
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cMLEP04010C 10 million/vial Inquire
cMLEP04015C 15 million/vial Inquire
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Product Description

CD4+ helper T cells express the CD4 co-receptor and play an important role in the adaptive immune system by assisting other white blood cells. These cells are activated when they are presented an antigen on the MHC class II molecule of an antigen-presenting cell (APC). Once activated, CD4+ helper T cells secrete lymphokines that assist in the activation of B cells to secrete antibodies that target specific microbes and assist in the activation of cytotoxic T cells to destroy infected target cells.

Human mobilized peripheral blood CD4+ cells are enriched from the total cell population using direct immunomagnetic anti-CD4 beads. All cell isolation components, including reagents, tubing sets, instruments, and buffers, are manufactured and controlled under an ISO 13485 certified quality system under FDA oversight. Cell culture procedures, including open manipulation of vials, final filling, and closure of finished products, are performed inside ISO 5 air quality processing chambers located within an FDA-registered cell manufacturing facility. Isolated primary cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used to collect and separate the cells are certified clinical grade. This item is for research use only.

More Information
Species Human
Disease State Healthy
Cell and Tissue Source Peripheral Blood
Product Type Primary Cells
Cell Type T Cells
Donor Attributes HIV-, HepB-, HepC-
Purity ≥85% by Flow Cytometry
Viability ≥80% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant ACD-A
Injections 240μg/kg Plerixafor the day before collection

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