Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD25 Depleted Cells, G-CSF + Plerixafor, Frozen
The ⍺-chain of the IL-2 receptor, CD25, is predominately expressed on activated T cells, but can also be found on inactive T cells, B cells, and myeloid cells.
Human mobilized peripheral blood CD25 T cells are depleted from the total cell population using direct immunomagnetic anti-CD25 beads. All cell isolation components, including reagents, tubing sets, instruments, and buffers, are manufactured and controlled under an ISO 13485 certified quality system under FDA oversight. Cell culture procedures, including open manipulation of vials, final filling, and closure of finished products, are performed inside ISO 5 air quality processing chambers located within an FDA-registered cell manufacturing facility. Isolated primary cells are characterized by flow cytometry to ensure a highly pure and viable cell population.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used to collect and separate the cells are certified clinical grade. This item is for research use only.
|Cell and Tissue Source||Peripheral Blood|
|Product Type||Primary Cells|
|Cell Type||Mononuclear Cells|
|Donor Attributes||HIV-, HepB-, HepC-|
|Viability||≥70% by Flow Cytometry|
|Contains||CryoStor™ CS10 (10% DMSO)|
|Injections||10μg/kg/day of G-CSF & 240μg/kg Plerixafor the day before collection|