Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD1c (BDCA-1)+ Cells, Plerixafor, Frozen | StemExpress

Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD1c (BDCA-1)+ Cells, Plerixafor, Frozen

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Category: Clinical Products
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cMLEP01C005C 5 million/vial Inquire
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Product Description

CD1c (BDCA-1) is expressed on myeloid dendritic cells (MDCs), also referred to as conventional dendritic cells, that also highly express MHC class II. Upon infection, MDCs become activated and promote adaptive immune responses. Additionally, CD1c is expressed on some B cells.

Human mobilized peripheral blood CD1c+ cells are enriched from the total cell population using indirect immunomagnetic anti-CD1c beads. All cell isolation components, including reagents, tubing sets, instruments, and buffers, are manufactured and controlled under an ISO 13485 certified quality system under FDA oversight. Cell culture procedures, including open manipulation of vials, final filling, and closure of finished products, are performed inside ISO 5 air quality processing chambers located within an FDA-registered cell manufacturing facility. Isolated primary cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used to collect and separate the cells are certified clinical grade. This item is for research use only.

More Information
Species Human
Disease State Healthy
Cell and Tissue Source Peripheral Blood
Product Type Primary Cells
Cell Type Dendritic Cells
Donor Attributes HIV-, HepB-, HepC-
Purity ≥85% by Flow Cytometry
Viability ≥70% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant ACD-A
Injections 240μg/kg Plerixafor the day before collection

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