Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD1c (BDCA-1)+ Cells, G-CSF + Plerixafor, Frozen
Category: Clinical Products
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|CD1c (BDCA-1) is expressed on myeloid dendritic cells (MDCs), also referred to as conventional dendritic cells, that also highly express MHC class II. Upon infection, MDCs become activated and promote adaptive immune responses. Additionally, CD1c is expressed on some B cells.
Human CD1c+ cells are isolated from the mononuclear cell fraction by means of indirect positive selection. Cells expressing CD1c are enriched from the mononuclear cell population using a CD1c-biotin antibody and anti-biotin immunomagnetic beads. CD1c+ cells are characterized by flow cytometry before cryopreservation to ensure a highly pure and viable cell population.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used in the collection and separation process are certified clinical grade. This item is for research use only.
|Cell and Tissue Source||Peripheral Blood|
|Product Type||Primary Cells|
|Cell Type||Dendritic Cells|
|Donor Attributes||HIV-, HepB-, HepC-|
|Purity||≥85% by Flow Cytometry|
|Viability||≥70% by Flow Cytometry|
|Contains||CryoStor™ CS10 (10% DMSO)|
|Injections||10μg/kg/day of G-CSF & 240μg/kg Plerixafor the day before collection|
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