Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD1c (BDCA-1)+ Cells, G-CSF + Plerixafor, Frozen

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Category: Clinical Products
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cMLEGP01C005C 5 million/vial Inquire
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Product Description
CD1c (BDCA-1) is expressed on myeloid dendritic cells (MDCs), also referred to as conventional dendritic cells, that also highly express MHC class II. Upon infection, MDCs become activated and promote adaptive immune responses. Additionally, CD1c is expressed on some B cells.

Human CD1c+ cells are isolated from the mononuclear cell fraction by means of indirect positive selection. Cells expressing CD1c are enriched from the mononuclear cell population using a CD1c-biotin antibody and anti-biotin immunomagnetic beads. CD1c+ cells are characterized by flow cytometry before cryopreservation to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used in the collection and separation process are certified clinical grade. This item is for research use only.
More Information
Species Human
Disease State Healthy
Cell and Tissue Source Peripheral Blood
Product Type Primary Cells
Cell Type Dendritic Cells
Donor Attributes HIV-, HepB-, HepC-
Purity ≥85% by Flow Cytometry
Viability ≥70% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant ACD-A
Injections 10μg/kg/day of G-CSF & 240μg/kg Plerixafor the day before collection

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