Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD19 Depleted Cells, Plerixafor, Frozen
Human B cells are lymphocytes that are characterized by the expression of CD19 on the cell surface. These cells are one of the main cell types involved in the humoral immune response. Upon activation, due to an encounter with an antigen, B cells will act as antigen-presenting cells (APCs), make antibodies against foreign antigens, and develop into memory B cells or plasma cells.
Human mobilized peripheral blood CD19 B cells are depleted from the mononuclear cell fraction by means of positive selection. Cells expressing CD19 are depleted from the mononuclear cell population using CD19 immunomagnetic beads. The CD19 depleted cells are characterized by flow cytometry before cryopreservation to ensure a highly pure and viable cell population.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used in the collection and separation process are certified clinical grade. This item is for research use only.
|Cell and Tissue Source||Peripheral Blood|
|Product Type||Primary Cells|
|Cell Type||Mononuclear Cells|
|Donor Attributes||HIV-, HepB-, HepC-|
|Viability||≥70% by Flow Cytometry|
|Contains||CryoStor™ CS10 (10% DMSO)|
|Injections||240μg/kg Plerixafor the day before collection|