Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD14+ Monocytes, G-CSF + Plerixafor, Frozen | StemExpress

Clinical Grade Non-Transfusable Mobilized Peripheral Blood CD14+ Monocytes, G-CSF + Plerixafor, Frozen

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Category: Clinical Products
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Product Description

Peripheral blood CD14+ monocytes originate in the bone marrow and move via the bloodstream to infected or damaged peripheral tissue. Once at the tissue, monocytes differentiate into specific tissue macrophage or dendritic cells. These cells are responsible for phagocytosis of foreign substances in the body and are capable of killing infected host cells via antibody-mediated cellular cytotoxicity.

Human mobilized peripheral blood CD14+ cells are enriched from the total cell population using direct immunomagnetic anti-CD14 beads. All cell isolation components, including reagents, tubing sets, instruments, and buffers, are manufactured and controlled under an ISO 13485 certified quality system under FDA oversight. Cell culture procedures, including open manipulation of vials, final filling, and closure of finished products, are performed inside ISO 5 air quality processing chambers located within an FDA-registered cell manufacturing facility. Isolated primary cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used to collect and separate the cells are certified clinical grade. This item is for research use only.

More Information
Species Human
Disease State Healthy
Cell and Tissue Source Peripheral Blood
Product Type Primary Cells
Cell Type Monocytes
Donor Attributes HIV-, HepB-, HepC-
Purity ≥90% by Flow Cytometry
Viability ≥80% by Flow Cytometry
Format Frozen
Contains CryoStor™ CS10 (10% DMSO)
Anticoagulant ACD-A
Injections 10μg/kg/day of G-CSF & 240μg/kg Plerixafor the day before collection

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