Clinical Grade Non-Transfusable Mobilized Leukopaks®, G-CSF + Plerixafor, Fresh
Clinical Grade Non-Transfusable Mobilized Leukopaks® are collected from healthy IRB consented donors that are injected with a combination of 10µg/kg/day of Granulocyte-Colony Stimulating Factor (G-CSF) and 240µg/kg of Plerixafor the day before collection, which stimulates the bone marrow to produce hematopoietic stem cells and mobilizes them into the bloodstream, prior to first day of collection. Mobilized mononuclear cells are collected by a trained technician using the Spectra Optia® Apheresis System one and two days post injection. After collection, mobilized Leukopaks® are checked by flow analysis to verify the percentage of granulocytes, lymphocytes, CD34+ cells, and cell viability.
• 2x10e10 TNCs/1 bag
• Enriched MNCs
• Enriched CD34+ cells
• Low hematocrit
• Low granulocytes
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols. All reagents and devices used in the collection process are certified clinical grade.
This item is for research use only.
|Cell and Tissue Source||Peripheral Blood|
|Donor Attributes||HIV-, HepB-, HepC-|
|Viability||≥90% by Flow Cytometry|